DNA looping by FokI: the impact of synapse geometry on loop topology at varied site orientations

Most restriction endonucleases, including FokI, interact with two copies of their recognition sequence before cutting DNA. On DNA with two sites they act in cis looping out the intervening DNA. While many restriction enzymes operate symmetrically at palindromic sites, FokI acts asymmetrically at a n...

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Detalles Bibliográficos
Autores principales: Rusling, David A., Laurens, Niels, Pernstich, Christian, Wuite, Gijs J. L., Halford, Stephen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367207/
https://www.ncbi.nlm.nih.gov/pubmed/22362745
http://dx.doi.org/10.1093/nar/gks183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367207/
https://www.ncbi.nlm.nih.gov/pubmed/22362745
http://dx.doi.org/10.1093/nar/gks183

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