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DNA looping by FokI: the impact of synapse geometry on loop topology at varied site orientations
Most restriction endonucleases, including FokI, interact with two copies of their recognition sequence before cutting DNA. On DNA with two sites they act in cis looping out the intervening DNA. While many restriction enzymes operate symmetrically at palindromic sites, FokI acts asymmetrically at a n...
Autores principales: | Rusling, David A., Laurens, Niels, Pernstich, Christian, Wuite, Gijs J. L., Halford, Stephen E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367207/ https://www.ncbi.nlm.nih.gov/pubmed/22362745 http://dx.doi.org/10.1093/nar/gks183 |
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