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Comparison of microfluidic digital PCR and conventional quantitative PCR for measuring copy number variation

One of the benefits of Digital PCR (dPCR) is the potential for unparalleled precision enabling smaller fold change measurements. An example of an assessment that could benefit from such improved precision is the measurement of tumour-associated copy number variation (CNV) in the cell free DNA (cfDNA...

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Detalles Bibliográficos
Autores principales: Whale, Alexandra S., Huggett, Jim F., Cowen, Simon, Speirs, Valerie, Shaw, Jacqui, Ellison, Stephen, Foy, Carole A., Scott, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367212/
https://www.ncbi.nlm.nih.gov/pubmed/22373922
http://dx.doi.org/10.1093/nar/gks203