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Combination of Sleeping Beauty transposition and chemically induced dimerization selection for robust production of engineered cells

The main methods for producing genetically engineered cells use viral vectors for which safety issues and manufacturing costs remain a concern. In addition, selection of desired cells typically relies on the use of cytotoxic drugs with long culture times. Here, we introduce an efficient non-viral ap...

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Detalles Bibliográficos
Autores principales: Kacherovsky, Nataly, Harkey, Michael A., Blau, C. Anthony, Giachelli, Cecilia M., Pun, Suzie H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367214/
https://www.ncbi.nlm.nih.gov/pubmed/22402491
http://dx.doi.org/10.1093/nar/gks213