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Combination of Sleeping Beauty transposition and chemically induced dimerization selection for robust production of engineered cells
The main methods for producing genetically engineered cells use viral vectors for which safety issues and manufacturing costs remain a concern. In addition, selection of desired cells typically relies on the use of cytotoxic drugs with long culture times. Here, we introduce an efficient non-viral ap...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367214/ https://www.ncbi.nlm.nih.gov/pubmed/22402491 http://dx.doi.org/10.1093/nar/gks213 |