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Thrombospondin-1 in Early Flow-Related Remodeling of Mesenteric Arteries from Young Normotensive and Spontaneously Hypertensive Rats

We tested the hypotheses that TSP-1 participates in the initiation of remodeling of small muscular arteries in response to altered blood flow and that the N-terminal domain of TSP-1 (hepI) can reverse the pathological inward remodeling of resistance arteries from SHR. We measured (1) changes in gene...

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Detalles Bibliográficos
Autores principales: Lemkens, P, Boari, GEM, Fazzi, GE, Janssen, GMJ, Murphy-Ullrich, JE, Schiffers, PMH, De Mey, JGR
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367304/
https://www.ncbi.nlm.nih.gov/pubmed/22670160
http://dx.doi.org/10.2174/1874192401206010050