Heart repair by reprogramming non-myocytes with cardiac transcription factors

The adult mammalian heart possesses little regenerative potential following injury. Fibrosis due to activation of cardiac fibroblasts impedes cardiac regeneration and contributes to loss of contractile function, pathological remodeling and susceptibility to arrhythmias. Cardiac fibroblasts account f...

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Detalles Bibliográficos
Autores principales: Song, Kunhua, Nam, Young-Jae, Luo, Xiang, Qi, Xiaoxia, Tan, Wei, Huang, Guo N., Acharya, Asha, Smith, Christopher L., Tallquist, Michelle D., Neilson, Eric G., Hill, Joseph A., Bassel-Duby, Rhonda, Olson, Eric N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367390/
https://www.ncbi.nlm.nih.gov/pubmed/22660318
http://dx.doi.org/10.1038/nature11139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367390/
https://www.ncbi.nlm.nih.gov/pubmed/22660318
http://dx.doi.org/10.1038/nature11139

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