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Efficiency of drug delivery enhanced by acoustic pressure during blood–brain barrier disruption induced by focused ultrasound

PURPOSE: We evaluated the delivery efficiency of intravenously injected large molecular agents, before and after disruption of the blood–brain barrier (BBB-D), induced by focused ultrasound (FUS) using various acoustic parameters. MATERIALS AND METHODS: Male Sprague-Dawley rats were injected intrave...

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Detalles Bibliográficos
Autores principales: Yang, Feng-Yi, Lee, Pei-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367490/
https://www.ncbi.nlm.nih.gov/pubmed/22679368
http://dx.doi.org/10.2147/IJN.S31675