Self-assembled squalenoyl-cytarabine nanostructures as a potent nanomedicine for treatment of leukemic diseases

BACKGROUND: In this investigation, the antileukemic activity of a new nanomedicine based on the conjugation of 1,1′,2-tris-nor-squalenic acid with cytarabine (Ara-C) was evaluated. METHODS: Squalenoyl-Ara-C conjugate (Sq-Ara-C) self-assembled nanosystems were obtained by the nanoprecipitation method...

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Detalles Bibliográficos
Autores principales: Cosco, Donato, Rocco, Flavio, Ceruti, Maurizio, Vono, Margherita, Fresta, Massimo, Paolino, Donatella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367491/
https://www.ncbi.nlm.nih.gov/pubmed/22679366
http://dx.doi.org/10.2147/IJN.S28114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367491/
https://www.ncbi.nlm.nih.gov/pubmed/22679366
http://dx.doi.org/10.2147/IJN.S28114

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