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Self-assembled squalenoyl-cytarabine nanostructures as a potent nanomedicine for treatment of leukemic diseases

BACKGROUND: In this investigation, the antileukemic activity of a new nanomedicine based on the conjugation of 1,1′,2-tris-nor-squalenic acid with cytarabine (Ara-C) was evaluated. METHODS: Squalenoyl-Ara-C conjugate (Sq-Ara-C) self-assembled nanosystems were obtained by the nanoprecipitation method...

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Detalles Bibliográficos
Autores principales:	Cosco, Donato, Rocco, Flavio, Ceruti, Maurizio, Vono, Margherita, Fresta, Massimo, Paolino, Donatella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2012
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367491/ https://www.ncbi.nlm.nih.gov/pubmed/22679366 http://dx.doi.org/10.2147/IJN.S28114

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