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Design of cationic nanostructured heterolipid matrices for ocular delivery of methazolamide

Solid lipid nanoparticles (SLNs) formulated from one type of lipid (homolipid) suffer from low drug encapsulation and drug bursting due to crystallization of the lipid into the more ordered β modification, which leads to decreased drug entrapment and faster drug release. This study assessed the feas...

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Detalles Bibliográficos
Autores principales: Youshia, John, Kamel, Amany O, El Shamy, Abdelhameed, Mansour, Samar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367493/
https://www.ncbi.nlm.nih.gov/pubmed/22679362
http://dx.doi.org/10.2147/IJN.S28307