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Glucose-induced posttranslational activation of protein phosphatases PP2A and PP1 in yeast

The protein phosphatases PP2A and PP1 are major regulators of a variety of cellular processes in yeast and other eukaryotes. Here, we reveal that both enzymes are direct targets of glucose sensing. Addition of glucose to glucose-deprived yeast cells triggered rapid posttranslational activation of bo...

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Detalles Bibliográficos
Autores principales: Castermans, Dries, Somers, Ils, Kriel, Johan, Louwet, Wendy, Wera, Stefaan, Versele, Matthias, Janssens, Veerle, Thevelein, Johan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367521/
https://www.ncbi.nlm.nih.gov/pubmed/22290422
http://dx.doi.org/10.1038/cr.2012.20