Mitochondrial Physiology and Gene Expression Analyses Reveal Metabolic and Translational Dysregulation in Oocyte-Induced Somatic Nuclear Reprogramming

While reprogramming a foreign nucleus after somatic cell nuclear transfer (SCNT), the enucleated oocyte (ooplasm) must signal that biomass and cellular requirements changed compared to the nucleus donor cell. Using cells expressing nuclear-encoded but mitochondria-targeted EGFP, a strategy was devel...

Descripción completa

Detalles Bibliográficos
Autores principales: Esteves, Telma C., Psathaki, Olympia E., Pfeiffer, Martin J., Balbach, Sebastian T., Zeuschner, Dagmar, Shitara, Hiroshi, Yonekawa, Hiromichi, Siatkowski, Marcin, Fuellen, Georg, Boiani, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367913/
https://www.ncbi.nlm.nih.gov/pubmed/22693623
http://dx.doi.org/10.1371/journal.pone.0036850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367913/
https://www.ncbi.nlm.nih.gov/pubmed/22693623
http://dx.doi.org/10.1371/journal.pone.0036850

Ejemplares similares