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A Novel RNAi Lethality Rescue Screen to Identify Regulators of Adipogenesis

Adipogenesis, the differentiation of fibroblast-like mesenchymal stem cells into mature adipocytes, is tightly regulated by a complex cascade of transcription factors, including the nuclear receptor Peroxisome proliferator activator receptor γ (PPARγ). RNAi-mediated knock down libraries may present...

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Detalles Bibliográficos
Autores principales: van Beekum, Olivier, Gao, Yuan, Berger, Ruud, Koppen, Arjen, Kalkhoven, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367974/
https://www.ncbi.nlm.nih.gov/pubmed/22679485
http://dx.doi.org/10.1371/journal.pone.0037680