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N-acetylcysteine reduces oxidative stress in sickle cell patients

Oxidative stress is of importance in the pathophysiology of sickle cell disease (SCD). In this open label randomized pilot study the effects of oral N-acetylcysteine (NAC) on phosphatidylserine (PS) expression as marker of cellular oxidative damage (primary end point), and markers of hemolysis, coag...

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Detalles Bibliográficos
Autores principales: Nur, Erfan, Brandjes, Dees P., Teerlink, Tom, Otten, Hans-Martin, Oude Elferink, Ronald P. J., Muskiet, Frits, Evers, Ludo M., ten Cate, Hugo, Biemond, Bart J., Duits, Ashley J., Schnog, John-John B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368118/
https://www.ncbi.nlm.nih.gov/pubmed/22318468
http://dx.doi.org/10.1007/s00277-011-1404-z