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Transgenerational Epigenetic Inheritance of Longevity in C. elegans

Chromatin modifiers regulate lifespan in several organisms, raising the question of whether changes in chromatin states in the parental generation could be incompletely reprogrammed in the next generation and thereby affect the lifespan of descendents. The histone H3 lysine 4 trimethylation (H3K4me3...

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Detalles Bibliográficos
Autores principales: Greer, Eric L., Maures, Travis J., Ucar, Duygu, Hauswirth, Anna G., Mancini, Elena, Lim, Jana P., Benayoun, Bérénice A., Shi, Yang, Brunet, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368121/
https://www.ncbi.nlm.nih.gov/pubmed/22012258
http://dx.doi.org/10.1038/nature10572