Identity-by-Descent-Based Phasing and Imputation in Founder Populations Using Graphical Models

Accurate knowledge of haplotypes, the combination of alleles co-residing on a single copy of a chromosome, enables powerful gene mapping and sequence imputation methods. Since humans are diploid, haplotypes must be derived from genotypes by a phasing process. In this study, we present a new computat...

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Detalles Bibliográficos
Autores principales: Palin, Kimmo, Campbell, Harry, Wright, Alan F, Wilson, James F, Durbin, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368215/
https://www.ncbi.nlm.nih.gov/pubmed/22006673
http://dx.doi.org/10.1002/gepi.20635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368215/
https://www.ncbi.nlm.nih.gov/pubmed/22006673
http://dx.doi.org/10.1002/gepi.20635

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