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Paradoxical Effects of Rapamycin on Experimental House Dust Mite-Induced Asthma

The mammalian target of rapamycin (mTOR) modulates immune responses and cellular proliferation. The objective of this study was to assess whether inhibition of mTOR with rapamycin modifies disease severity in two experimental murine models of house dust mite (HDM)-induced asthma. In an induction mod...

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Detalles Bibliográficos
Autores principales: Fredriksson, Karin, Fielhaber, Jill A., Lam, Jonathan K., Yao, Xianglan, Meyer, Katharine S., Keeran, Karen J., Zywicke, Gayle J., Qu, Xuan, Yu, Zu-Xi, Moss, Joel, Kristof, Arnold S., Levine, Stewart J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368343/
https://www.ncbi.nlm.nih.gov/pubmed/22685525
http://dx.doi.org/10.1371/journal.pone.0033984