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Reactivity of Biarylazacyclooctynones in Copper-Free Click Chemistry
[Image: see text] The 1,3-dipolar cycloaddition of cyclooctynes with azides, also called “copper-free click chemistry”, is a bioorthogonal reaction with widespread applications in biological discovery. The kinetics of this reaction are of paramount importance for studies of dynamic processes, partic...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368396/ https://www.ncbi.nlm.nih.gov/pubmed/22553995 http://dx.doi.org/10.1021/ja3000936 |