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Reactivity of Biarylazacyclooctynones in Copper-Free Click Chemistry

[Image: see text] The 1,3-dipolar cycloaddition of cyclooctynes with azides, also called “copper-free click chemistry”, is a bioorthogonal reaction with widespread applications in biological discovery. The kinetics of this reaction are of paramount importance for studies of dynamic processes, partic...

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Detalles Bibliográficos
Autores principales: Gordon, Chelsea G., Mackey, Joel L., Jewett, John C., Sletten, Ellen M., Houk, K. N., Bertozzi, Carolyn R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368396/
https://www.ncbi.nlm.nih.gov/pubmed/22553995
http://dx.doi.org/10.1021/ja3000936