Can regional spreading of amyotrophic lateral sclerosis motor symptoms be explained by prion-like propagation?

Progressive accumulation of specific misfolded protein is a defining feature of amyotrophic lateral sclerosis (ALS), similarly seen in Alzheimer disease, Parkinson disease, Huntington disease and Creutzfeldt–Jakob disease. The intercellular transfer of inclusions made of tau, α-synuclein and hunting...

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Detalles Bibliográficos
Autores principales: Kanouchi, Tadashi, Ohkubo, Takuya, Yokota, Takanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Group 2012
Materias:
Neurodegeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368493/
https://www.ncbi.nlm.nih.gov/pubmed/22544947
http://dx.doi.org/10.1136/jnnp-2011-301826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368493/
https://www.ncbi.nlm.nih.gov/pubmed/22544947
http://dx.doi.org/10.1136/jnnp-2011-301826

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