Cargando…
Can regional spreading of amyotrophic lateral sclerosis motor symptoms be explained by prion-like propagation?
Progressive accumulation of specific misfolded protein is a defining feature of amyotrophic lateral sclerosis (ALS), similarly seen in Alzheimer disease, Parkinson disease, Huntington disease and Creutzfeldt–Jakob disease. The intercellular transfer of inclusions made of tau, α-synuclein and hunting...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BMJ Group
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368493/ https://www.ncbi.nlm.nih.gov/pubmed/22544947 http://dx.doi.org/10.1136/jnnp-2011-301826 |