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Using default constraints of the spindle assembly checkpoint to estimate the associated chemical rates
BACKGROUND: Default activation of the spindle assembly checkpoint provides severe constraints on the underlying biochemical activation rates: on one hand, the cell cannot divide before all chromosomes are aligned, but on the other hand, when they are ready, the separation is quite fast, lasting a fe...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368725/ https://www.ncbi.nlm.nih.gov/pubmed/22260411 http://dx.doi.org/10.1186/2046-1682-5-1 |