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Using default constraints of the spindle assembly checkpoint to estimate the associated chemical rates

BACKGROUND: Default activation of the spindle assembly checkpoint provides severe constraints on the underlying biochemical activation rates: on one hand, the cell cannot divide before all chromosomes are aligned, but on the other hand, when they are ready, the separation is quite fast, lasting a fe...

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Detalles Bibliográficos
Autores principales: Dao Duc, Khanh, Holcman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368725/
https://www.ncbi.nlm.nih.gov/pubmed/22260411
http://dx.doi.org/10.1186/2046-1682-5-1