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Genetic variations in APPL2 are associated with overweight and obesity in a Chinese population with normal glucose tolerance
BACKGROUND: APPL1 and APPL2 are two adaptor proteins, which can mediate adiponectin signaling via binding to N terminus of adiponectin receptors in muscle cells. Genes encoding adiponectin and adiponectin receptors contribute to insulin resistance and the risk of obesity, and genetic variants of APP...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368742/ https://www.ncbi.nlm.nih.gov/pubmed/22462604 http://dx.doi.org/10.1186/1471-2350-13-22 |