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Genetic variations in APPL2 are associated with overweight and obesity in a Chinese population with normal glucose tolerance

BACKGROUND: APPL1 and APPL2 are two adaptor proteins, which can mediate adiponectin signaling via binding to N terminus of adiponectin receptors in muscle cells. Genes encoding adiponectin and adiponectin receptors contribute to insulin resistance and the risk of obesity, and genetic variants of APP...

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Detalles Bibliográficos
Autores principales: Jiang, Shan, Fang, Qichen, Yu, Weihui, Zhang, Rong, Hu, Cheng, Dong, Kun, Bao, Yuqian, Wang, Chen, Xiang, Kunsan, Jia, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368742/
https://www.ncbi.nlm.nih.gov/pubmed/22462604
http://dx.doi.org/10.1186/1471-2350-13-22