The PPAR-gamma agonist pioglitazone protects cortical neurons from inflammatory mediators via improvement in peroxisomal function

BACKGROUND: Inflammation is known to play a pivotal role in mediating neuronal damage and axonal injury in a variety of neurodegenerative disorders. Among the range of inflammatory mediators, nitric oxide and hydrogen peroxide are potent neurotoxic agents. Recent evidence has suggested that oligoden...

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Detalles Bibliográficos
Autores principales: Gray, Elizabeth, Ginty, Mark, Kemp, Kevin, Scolding, Neil, Wilkins, Alastair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368767/
https://www.ncbi.nlm.nih.gov/pubmed/22480361
http://dx.doi.org/10.1186/1742-2094-9-63

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368767/
https://www.ncbi.nlm.nih.gov/pubmed/22480361
http://dx.doi.org/10.1186/1742-2094-9-63

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