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The PPAR-gamma agonist pioglitazone protects cortical neurons from inflammatory mediators via improvement in peroxisomal function

BACKGROUND: Inflammation is known to play a pivotal role in mediating neuronal damage and axonal injury in a variety of neurodegenerative disorders. Among the range of inflammatory mediators, nitric oxide and hydrogen peroxide are potent neurotoxic agents. Recent evidence has suggested that oligoden...

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Detalles Bibliográficos
Autores principales:	Gray, Elizabeth, Ginty, Mark, Kemp, Kevin, Scolding, Neil, Wilkins, Alastair
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368767/ https://www.ncbi.nlm.nih.gov/pubmed/22480361 http://dx.doi.org/10.1186/1742-2094-9-63

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