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Connective tissue growth factor in tumor pathogenesis

Key roles for connective tissue growth factor (CTGF/CCN2) are demonstrated in the wound repair process where it promotes myofibroblast differentiation and angiogenesis. Similar mechanisms are active in tumor-reactive stroma where CTGF is expressed. Other potential roles include prevention of hypoxia...

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Detalles Bibliográficos
Autores principales: Jacobson, Annica, Cunningham, Janet L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368788/
https://www.ncbi.nlm.nih.gov/pubmed/23259759
http://dx.doi.org/10.1186/1755-1536-5-S1-S8