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Reversal of transforming growth factor-β induced epithelial-to-mesenchymal transition and the ZEB proteins

BACKGROUND: The dynamic process of epithelial-to-mesenchymal transition (EMT) is a causal event in kidney fibrosis. This cellular phenotypic transition involves activation of transcriptional responses and remodeling of cellular structures to change cellular function. The molecular mechanisms that di...

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Detalles Bibliográficos
Autores principales: Das, Shreyasi, Becker, Bryan N, Hoffmann, F Michael, Mertz, Janet E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368790/
https://www.ncbi.nlm.nih.gov/pubmed/23259633
http://dx.doi.org/10.1186/1755-1536-5-S1-S28