CTGF is a central mediator of tissue remodeling and fibrosis and its inhibition can reverse the process of fibrosis

CTGF is a secreted matricellular protein with very complex biology. It has been shown to modulate many signaling pathways leading to cell adhesion and migration, angiogenesis, myofibroblast activation, and extracellular matrix deposition and remodeling, which together lead to tissue remodeling and f...

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Detalles Bibliográficos
Autores principales: Lipson, Kenneth E, Wong, Carol, Teng, Yuchin, Spong, Suzanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368796/
https://www.ncbi.nlm.nih.gov/pubmed/23259531
http://dx.doi.org/10.1186/1755-1536-5-S1-S24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368796/
https://www.ncbi.nlm.nih.gov/pubmed/23259531
http://dx.doi.org/10.1186/1755-1536-5-S1-S24

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