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(α,α-dimethyl)glycyl (dmg) PNAs: Achiral PNA analogs that form stronger hybrids with cDNA relative to isosequential RNA
The design and facile synthesis of sterically constrained new analogs of PNA having gem-dimethyl substitutions on glycine (dmg-PNA-T) is presented. The PNA oligomers [aminoethyl dimethylglycyl (aedmg) and aminopropyl dimethylglycyl (apdmg)] synthesized from the monomers 6 and 12) effected remarkable...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368815/ https://www.ncbi.nlm.nih.gov/pubmed/22679528 http://dx.doi.org/10.4161/adna.19185 |