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Two Nuclear Localization Signals in USP1 Mediate Nuclear Import of the USP1/UAF1 Complex
The human deubiquitinase USP1 plays important roles in cancer-related processes, such as the DNA damage response, and the maintenance of the undifferentiated state of osteosarcoma cells. USP1 deubiquitinase activity is critically regulated by its interaction with the WD40 repeat-containing protein U...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368879/ https://www.ncbi.nlm.nih.gov/pubmed/22701671 http://dx.doi.org/10.1371/journal.pone.0038570 |