Acute Progression of BCR-FGFR1 Induced Murine B-Lympho/Myeloproliferative Disorder Suggests Involvement of Lineages at the Pro-B Cell Stage

Constitutive activation of FGFR1, through rearrangement with various dimerization domains, leads to atypical myeloproliferative disorders where, although T cell lymphoma are common, the BCR-FGFR1 chimeric kinase results in CML-like leukemia. As with the human disease, mouse bone marrow transduction/...

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Detalles Bibliográficos
Autores principales: Ren, MingQiang, Tidwell, Josephine A., Sharma, Suash, Cowell, John K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368885/
https://www.ncbi.nlm.nih.gov/pubmed/22701616
http://dx.doi.org/10.1371/journal.pone.0038265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368885/
https://www.ncbi.nlm.nih.gov/pubmed/22701616
http://dx.doi.org/10.1371/journal.pone.0038265

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