The ROS Scavenger, NAC, Regulates Hepatic Vα14iNKT Cells Signaling during Fas mAb-Dependent Fulminant Liver Failure

Uncontrolled systemic activation of the immune system is an early initiating event that leads to development of acute fulminant liver failure (FLF) in mice after treatment with agonistic Fas mAb. In this study, we demonstrate that treatment of mice with N-acetylcysteine (NAC), an ROS scavenger and g...

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Detalles Bibliográficos
Autores principales: Downs, Isaac, Liu, Jianfeng, Aw, Tak Yee, Adegboyega, Patrick A., Ajuebor, Maureen N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368940/
https://www.ncbi.nlm.nih.gov/pubmed/22701598
http://dx.doi.org/10.1371/journal.pone.0038051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368940/
https://www.ncbi.nlm.nih.gov/pubmed/22701598
http://dx.doi.org/10.1371/journal.pone.0038051

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