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Integrin α9β1 promotes malignant tumor growth and metastasis by potentiating epithelial-mesenchymal transition

The integrin α9β1 binds a number of extracellular matrix components to mediate cell adhesion, migration and tissue invasion. Although expressed in variety of normal human cells including endothelium, it is also expressed in cancer cells. We have previously shown that α9β1 binds VEGF-A to facilitate...

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Detalles Bibliográficos
Autores principales: Gupta, Shiv K, Oommen, Saji, Aubry, Marie-Christine, Williams, Brian P., Vlahakis, Nicholas E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368989/
https://www.ncbi.nlm.nih.gov/pubmed/22370635
http://dx.doi.org/10.1038/onc.2012.41