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In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes

The reprogramming of adult cells into pluripotent cells or directly into alternative adult cell types holds great promise for regenerative medicine. We reported that cardiac fibroblasts, which represent 50% of the cells in the mammalian heart, can be directly reprogrammed to adult cardiomyocyte-like...

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Detalles Bibliográficos
Autores principales: Qian, Li, Huang, Yu, Spencer, C. Ian, Foley, Amy, Vedantham, Vasanth, Liu, Lei, Conway, Simon J., Fu, Ji-dong, Srivastava, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369107/
https://www.ncbi.nlm.nih.gov/pubmed/22522929
http://dx.doi.org/10.1038/nature11044