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Lack of CC chemokine ligand 2 differentially affects inflammation and fibrosis according to the genetic background in a murine model of steatohepatitis

Expression of CCL2 (CC chemokine ligand 2) (or monocyte chemoattractant protein-1) regulates inflammatory cell infiltration in the liver and adipose tissue, favouring steatosis. However, its role in the pathogenesis of steatohepatitis is still uncertain. In the present study, we investigated the dev...

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Detalles Bibliográficos
Autores principales: Galastri, Sara, Zamara, Elena, Milani, Stefano, Novo, Erica, Provenzano, Angela, Delogu, Wanda, Vizzutti, Francesco, Sutti, Salvatore, Locatelli, Irene, Navari, Nadia, Vivoli, Elisa, Caligiuri, Alessandra, Pinzani, Massimo, Albano, Emanuele, Parola, Maurizio, Marra, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369401/
https://www.ncbi.nlm.nih.gov/pubmed/22545719
http://dx.doi.org/10.1042/CS20110515