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Polymer-Based Delivery of Glucagon-Like Peptide-1 for the Treatment of Diabetes

The incretin hormones, glucagon-like peptide-1 (GLP-1) and its receptor agonist (exendin-4), are well known for glucose homeostasis, insulinotropic effect, and effects on weight loss and food intake. However, due to the rapid degradation of GLP-1 by dipeptidylpeptidase-IV (DPP-IV) enzyme and renal e...

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Detalles Bibliográficos
Autores principales: Kim, Pyung-Hwan, Kim, Sung Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369441/
https://www.ncbi.nlm.nih.gov/pubmed/22701182
http://dx.doi.org/10.5402/2012/340632