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Polymer-Based Delivery of Glucagon-Like Peptide-1 for the Treatment of Diabetes
The incretin hormones, glucagon-like peptide-1 (GLP-1) and its receptor agonist (exendin-4), are well known for glucose homeostasis, insulinotropic effect, and effects on weight loss and food intake. However, due to the rapid degradation of GLP-1 by dipeptidylpeptidase-IV (DPP-IV) enzyme and renal e...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scholarly Research Network
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369441/ https://www.ncbi.nlm.nih.gov/pubmed/22701182 http://dx.doi.org/10.5402/2012/340632 |