Pharmacological Unmasking Microarray Approach-Based Discovery of Novel DNA Methylation Markers for Hepatocellular Carcinoma

DNA methylation is one of the main epigenetic mechanisms and hypermethylation of CpG islands at tumor suppressor genes switches off these genes. To find novel DNA methylation markers in hepatocellular carcinoma (HCC), we performed pharmacological unmasking (treatment with 5-aza-2'-deoxycytidine...

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Detalles Bibliográficos
Autores principales: Jung, Namhee, Won, Jae Kyung, Kim, Baek-Hui, Suh, Kyung Suk, Jang, Ja-June, Kang, Gyeong Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369444/
https://www.ncbi.nlm.nih.gov/pubmed/22690089
http://dx.doi.org/10.3346/jkms.2012.27.6.594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369444/
https://www.ncbi.nlm.nih.gov/pubmed/22690089
http://dx.doi.org/10.3346/jkms.2012.27.6.594

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