Tau and Caspase 3 as Targets for Neuroprotection

The peptide drug candidate NAP (davunetide) has demonstrated protective effects in various in vivo and in vitro models of neurodegeneration. NAP was shown to reduce tau hyperphosphorylation as well as to prevent caspase-3 activation and cytochrome-3 release from mitochondria, both characteristic of...

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Detalles Bibliográficos
Autores principales: Idan-Feldman, Anat, Ostritsky, Regina, Gozes, Illana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369463/
https://www.ncbi.nlm.nih.gov/pubmed/22693678
http://dx.doi.org/10.1155/2012/493670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369463/
https://www.ncbi.nlm.nih.gov/pubmed/22693678
http://dx.doi.org/10.1155/2012/493670

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