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Inhibition of Gene Expression of Organic Cation/Carnitine Transporter and Antioxidant Enzymes in Oxazaphosphorines-Induced Acute Cardiomyopathic Rat Models

It is well documented that high therapeutic doses of oxazaphosphorines, cyclophosphamide (CP) and ifosfamide (IFO), are associated with cardiomyopathy. This study investigated whether oxazaphosphorines alter the expression of organic cation/carnitine transporter (OCTN2) and antioxidant genes and if...

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Detalles Bibliográficos
Autores principales: Sayed-Ahmed, Mohamed M., Aldelemy, Meshan Lafi, Hafez, Mohamed M., Al-Shabanah, Othman A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369488/
https://www.ncbi.nlm.nih.gov/pubmed/22701146
http://dx.doi.org/10.1155/2012/452902