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Overexpression of Delayed Rectifier K(+) Channels Promotes In situ Proliferation of Leukocytes in Rat Kidneys with Advanced Chronic Renal Failure

Leukocytes, such as lymphocytes and macrophages, predominantly express delayed rectifier K(+) channels (Kv1.3), and the channels play crucial roles in the activation and proliferation of the cells. Since lymphocytes are activated in patients with end-stage renal disease (ESRD), the channels expresse...

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Detalles Bibliográficos
Autores principales: Kazama, Itsuro, Maruyama, Yoshio, Endo, Yasuhiro, Toyama, Hiroaki, Ejima, Yutaka, Matsubara, Mitsunobu, Kurosawa, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369525/
https://www.ncbi.nlm.nih.gov/pubmed/22701172
http://dx.doi.org/10.1155/2012/581581