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Nuclear Translocation of Acinetobacter baumannii Transposase Induces DNA Methylation of CpG Regions in the Promoters of E-cadherin Gene

Nuclear targeting of bacterial proteins has emerged as a pathogenic mechanism whereby bacterial proteins induce host cell pathology. In this study, we examined nuclear targeting of Acinetobacter baumannii transposase (Tnp) and subsequent epigenetic changes in host cells. Tnp of A. baumannii ATCC 179...

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Detalles Bibliográficos
Autores principales: Moon, Dong Chan, Choi, Chul Hee, Lee, Su Man, Lee, Jung Hwa, Kim, Seung Il, Kim, Dong Sun, Lee, Je Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369853/
https://www.ncbi.nlm.nih.gov/pubmed/22685614
http://dx.doi.org/10.1371/journal.pone.0038974