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The 3′ Splice Site of Influenza A Segment 7 mRNA Can Exist in Two Conformations: A Pseudoknot and a Hairpin

The 3′ splice site of influenza A segment 7 is used to produce mRNA for the M2 ion-channel protein, which is critical to the formation of viable influenza virions. Native gel analysis, enzymatic/chemical structure probing, and oligonucleotide binding studies of a 63 nt fragment, containing the 3′ sp...

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Detalles Bibliográficos
Autores principales: Moss, Walter N., Dela-Moss, Lumbini I., Kierzek, Elzbieta, Kierzek, Ryszard, Priore, Salvatore F., Turner, Douglas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369869/
https://www.ncbi.nlm.nih.gov/pubmed/22685560
http://dx.doi.org/10.1371/journal.pone.0038323