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Silencing of Rac1 expression via RNA interference inhibits retinal neovascularization in rats

PURPOSE: To investigate the inhibitory effect of Ras-related C3 botulinum toxin substrate 1-small interfering RNA (Rac1-siRNA) on retinal neovascularization in a rat model. METHODS: Rac1-short hairpin RNA (shRNA) was synthesized, constructed, and transfected into HeLa cells. Reverse transcription po...

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Detalles Bibliográficos
Autores principales: Li, Juanjuan, Li, Yunpeng, Zhang, Meixia, Hu, Zhulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369893/
https://www.ncbi.nlm.nih.gov/pubmed/22690113