Experimental murine myopia induces collagen type Iα1 (COL1A1) DNA methylation and altered COL1A1 messenger RNA expression in sclera

PURPOSE: To investigate whether myopia development is associated with changes of scleral DNA methylation in cytosine-phosphate-guanine (CpG) sites in the collagen 1A1 (COL1A1) promoter and messenger RNA (mRNA) levels following murine form deprivation myopia. METHODS: Fifty-seven C57BL/6 mice (postna...

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Detalles Bibliográficos
Autores principales: Zhou, Xiangtian, Ji, Fengtao, An, Jianhong, Zhao, Fuxin, Shi, Fanjun, Huang, Furong, Li, Yuan, Jiao, Shiming, Yan, Dongsheng, Chen, Xiaoyan, Chen, JiangFan, Qu, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369898/
https://www.ncbi.nlm.nih.gov/pubmed/22690110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369898/
https://www.ncbi.nlm.nih.gov/pubmed/22690110

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