Constitutively Active Canonical NF-κB Pathway Induces Severe Bone Loss in Mice

Physiologic osteoclastogenesis entails activation of multiple signal transduction pathways distal to the cell membrane receptor RANK. However, atypical osteoclastogenesis driven by pro-inflammatory stimuli has been described. We have reported recently a novel mechanism whereby endogenous mutational...

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Detalles Bibliográficos
Autores principales: Otero, Jesse E., Chen, Tim, Zhang, Kaihua, Abu-Amer, Yousef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369901/
https://www.ncbi.nlm.nih.gov/pubmed/22685599
http://dx.doi.org/10.1371/journal.pone.0038694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369901/
https://www.ncbi.nlm.nih.gov/pubmed/22685599
http://dx.doi.org/10.1371/journal.pone.0038694

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