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Sterol Intermediates of Cholesterol Biosynthesis Inhibit Hair Growth and Trigger an Innate Immune Response in Cicatricial Alopecia

Primary cicatricial alopecia (PCA) is a group of inflammatory hair disorders that cause scarring and permanent hair loss. Previous studies have implicated PPARγ, a transcription factor that integrates lipogenic and inflammatory signals, in the pathogenesis of PCA. However, it is unknown what trigger...

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Detalles Bibliográficos
Autores principales: Panicker, Sreejith P., Ganguly, Taneeta, Consolo, Mary, Price, Vera, Mirmirani, Paradi, Honda, Kord, Karnik, Pratima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369908/
https://www.ncbi.nlm.nih.gov/pubmed/22685570
http://dx.doi.org/10.1371/journal.pone.0038449