Human Herpesvirus 8 Interferon Regulatory Factor-Mediated BH3-Only Protein Inhibition via Bid BH3-B Mimicry

Viral replication efficiency is in large part governed by the ability of viruses to counteract pro-apoptotic signals induced by infection of host cells. For HHV-8, viral interferon regulatory factor-1 (vIRF-1) contributes to this process in part via inhibitory interactions with BH3-only protein (BOP...

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Detalles Bibliográficos
Autores principales: Choi, Young Bong, Sandford, Gordon, Nicholas, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369933/
https://www.ncbi.nlm.nih.gov/pubmed/22685405
http://dx.doi.org/10.1371/journal.ppat.1002748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369933/
https://www.ncbi.nlm.nih.gov/pubmed/22685405
http://dx.doi.org/10.1371/journal.ppat.1002748

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