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Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner
The blood vessels of cancerous tumours are leaky(1–3) and poorly organized(4–7). This can increase the interstitial fluid pressure (IFP) inside tumours and reduce blood supply to them, which impairs drug delivery(8–9). Anti-angiogenic therapies – which “normalize” the abnormal blood vessels in tumou...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370066/ https://www.ncbi.nlm.nih.gov/pubmed/22484912 http://dx.doi.org/10.1038/nnano.2012.45 |