Artesunate/dihydroartemisinin pharmacokinetics in acute falciparum malaria in pregnancy: absorption, bioavailability, disposition and disease effects

AIM: To determine if reported lower plasma concentrations of artemisinin derivatives for malaria in pregnancy result from reduced oral bioavailability, expanded volume of distribution or increased clearance. METHODS: In a sequentially assigned crossover treatment study, pregnant women with uncomplic...

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Detalles Bibliográficos
Autores principales: McGready, Rose, Phyo, Aung Pyae, Rijken, Marcus J, Tarning, Joel, Lindegardh, Niklas, Hanpithakpon, Warunee, Than, Hla Hla, Hlaing, Nathar, Zin, Naw Thida, Singhasivanon, Pratap, White, Nicholas J, Nosten, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2012
Materias:
Drugs in Pregnancy and Lactation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370352/
https://www.ncbi.nlm.nih.gov/pubmed/21950338
http://dx.doi.org/10.1111/j.1365-2125.2011.04103.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370352/
https://www.ncbi.nlm.nih.gov/pubmed/21950338
http://dx.doi.org/10.1111/j.1365-2125.2011.04103.x

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